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Ultimate Guide to Traveling with Portable Oxygen Concentrators

traveling with oxygen

Written By: Lisa Burkhart

March 20, 2025

EVERYTHING you need to know about Traveling with a Portable Oxygen Concentrator at a glance!

For individuals relying on oxygen therapy, traveling was once a challenge filled with restrictions and uncertainties but today traveling with portable oxygen concentrators has opened up the world for oxygen users. The fear of running out of oxygen or facing difficulties in transportation often discouraged many from exploring new destinations. However, advancements in portable oxygen concentrators (POCs) have made traveling safer and more accessible. These devices provide a continuous or pulse dose of oxygen, ensuring users can enjoy their journeys with confidence. With long-lasting batteries, AC power supplies for standard outlets, and DC power adapters for vehicle charging, traveling with portable oxygen concentrators have revolutionized life for oxygen users.

In this comprehensive guide, we will cover everything you need to know about traveling with a POC. From air travel regulations to road trip essentials, you’ll find valuable tips to make your trip stress-free and enjoyable. 

For personalized assistance call OxiMedical.com at 1-888-643-4921.

Planning Your Trip with a Portable Oxygen Concentrator

traveling with a portable oxygen concentratorCLICK HERE to download your FREE OXYGEN TRAVEL GUIDE!

Consult Your Doctor Before Traveling

Before setting off on your journey, schedule an appointment with your healthcare provider to discuss your travel plans. Your doctor can give you sound advice to ensure safe and stress-free travel. Consider the following:

  • Airplane Oxygen Adjustment: Cabin pressure at cruising altitude is equivalent to about 8,000 feet above sea level. Ask your doctor if adjustments to your oxygen levels are necessary to maintain proper saturation.
  • Climate Changes: Extreme temperatures or humidity at your destination can affect your breathing. Your doctor can recommend precautions to take.
  • Allergy Management: Traveling to new locations may expose you to unfamiliar allergens. Discuss taking antihistamines or other medications in advance.
  • Medication Supply: Always carry extra medication in case of unexpected delays. Keep them in your carry-on bag to avoid losing them in checked luggage.

Packing Checklist for Oxygen Users

Packing list for oxygen users

To ensure a smooth trip, prepare a checklist of essential items. Our suggested list includes:

Portable oxygen concentrator 

Fully charged extra batteries 

AC power supply 

DC power supply (for car charging)  

International outlet converter (if traveling abroad)  

External battery charger 

Extra nasal cannulas and tubing 

Alcohol wipes for cleaning cannulas 

Prescription and insurance documentation 

Airline-required paperwork

Air Travel with a Portable Oxygen Concentrator

At the Airport

Keep in mind that emotions affect your breathing so give yourself plenty of time to keep stress and anxiety at bay. Don’t be afraid to request mobility assistance if it will make your travel experience less taxing.

Bring snacks and plenty of water for your wait at the gate.

  • Arrive at the airport at least two hours before domestic flights and three hours before international flights to reduce stress.
  • Request wheelchair or cart assistance at least 48 hours before your flight if needed.
  • Stay hydrated—your lungs are 80% water, and dehydration can make breathing difficult.

TSA Screening

tsa with oxygen

  • If possible, disconnect from your POC and place it in the X-ray screening machine X-Ray screening isn’t harmful to your concentrator.
  • If you cannot safely disconnect from your oxygen, inform the TSA agent, who will conduct a manual inspection.
  • Bring sanitary wipes to clean your device after screening.
  • Check the TSA website or call 1-866-289-9673 if you have any questions about the screening process..

On the Plane

  • Different airlines have different requirements but generally, battery life must cover 150% of the total flight time 
  • Double check airline policies—extended-life batteries over 160Wh have recently become restricted by some airlines.
  • Confirm airline documentation requirements—some require a prescription, while others need physician documentation.
  • Check policies for all connecting airlines to ensure compliance.
  • All Portable Oxygen Concentrators from OxiMedical are FAA-approved for air travel and our respiratory specialists can assist you with travel necessities.

Traveling by Car with Portable Oxygen Concentrator

The flexibility of a portable oxygen concentrator allows for road trips without the worry of running out of oxygen. Each oxygen concentrator comes with a D/C power supply that plugs into the D/C outlet or cigarette lighter of your car or R/V. When plugged in the concentrator will run off of D/C power preserving battery life. Depending upon the electricity yield of your car outlet, the D/C power supply may also charge the battery too. Before you go on your trip, make a test run so you’ll know if your concentrator charges on D/C power or not. Here are some essential guidelines for car travel:

  • Never plug in your POC while the vehicle is off, as it may drain the car battery.
  • Avoid leaving your concentrator in the trunk. Extreme hot or cold temperatures can damage the electronics and affect the longevity of the sieve beds.
  • Secure your device on the floor or seat to prevent it falling or hitting the dash during sudden stops.
  • Ensure ventilation by keeping the device’s air intakes clear. Make sure jackets or blankets aren’t blocking the vents. Place the device away from seating cushions and floor mats as well.
  • Prohibiting smoking in the car is absolutely essential for oxygen safety.

Cruising with a Portable Oxygen Concentrator

Going on a cruise with oxygen

Ocean voyages can be fun and relaxing. They are also some of the most accommodating for those on oxygen. Be sure to follow these tips to ensure a smooth sailing experience:

  • Inform your cruise line in advance about your oxygen needs.
  • Confirm the types of power outlets on board to ensure proper charging compatibility. Ships that originate from Europe or Latin American destinations may require a power adapter.
  • Check with excursion providers to see what documentation is required for participation or transport.
  • Consider an external charger, if available for your concentrator, so you can charge spare batteries without interrupting your fun activities.

Train and Bus Travel with Portable Oxygen Concentrator

Train Travel

Train travel affords travelers the opportunity to relax and watch the beauty of the countryside go by. Overseas, train travel is as popular, if not more popular than air travel. It’s economical and fun. Contact your transport provider to learn about their requirements and resources for assistance.

  • Amtrak requires at least 4 hours of backup battery power in case of service delays.
  • Contact Amtrak at 1-800-872-7245 for specific policies.
  • You can read about their requirements here: Amtrak Use of Oxygen

Bus Travel

Bus travel is possibly one of the most challenging modes of transportation for oxygen users.

  • Greyhound permits portable oxygen concentrators, but, keep in mind, buses do not have charging ports.
  • Plan for overnight stops to recharge your batteries.
  • For more details, call 1-800-752-4841 or email ADA.support@greyhound.com.

Stay Safe While Exploring Your Destination

Most importantly, search the area online for the closest hospitals and doctors that are in your insurance network that you can visit in case of emergency. Also locate the nearest facilities that may have generators in case of power failure. Hospitals and fire or police stations are likely to have generator power in event of loss of electricity. 

While traveling, prioritize your health and safety by following these guidelines:

Stick to Your Schedule

  • Set reminders on your phone for medication and breathing exercises.

Check Air Quality

  • Monitor pollution or pollen levels at your destination. Wear a mask or cover your nose and mouth if needed.

Monitor the Weather

  • Extreme heat, cold, or humidity can impact breathing. Plan indoor activities if necessary.

Plan Downtime

  • Avoid overexertion by scheduling rest breaks and staying hydrated.
  • Carry a water bottle to prevent dehydration. Limit caffeine and alcohol, as they can worsen symptoms.

Be Mindful of Food Triggers

  • Avoid foods that may cause indigestion, GERD, or breathing difficulties.
  • Limit salt intake, as excess sodium can lead to fluid retention, making breathing harder.

Use Mobility Aids if Needed

  • Many hotels and local shops offer mobility rentals—don’t hesitate to use one if it helps conserve your energy.

Avoid Triggers Where You will be Staying

  • Aerosol air fresheners can be irritating to breathing passages.
  • Even pleasant smells such as potpourri, scented candles, or essential oils can be irritating to your lungs and should be avoided.
  • Bleach or other cleaners with noxious fumes can be hazardous to your lungs.
  • Ask your hosts to clean when you’re not in the room and to use natural cleaners if possible. They should also ventilate well when they are finished.
  • If you’re staying in a private home, ask to have your room sequestered from pets to avoid dander and other allergens.
  • Try to arrange to stay on lower floors so that you can evacuate easier in the event of an emergency. 
  • Request hypoallergenic bedding, if available.
  • Avoid any feather filled bedding which can cause allergic reactions.
  • Bring your own pillow or pillowcase, if preferred.

Most Importantly – Have a Great Time!

With proper planning, traveling with oxygen can be stress-free and enjoyable! Whether you’re taking a cross-country road trip, flying to a tropical paradise, or embarking on a cruise, your portable oxygen concentrator makes it possible to explore the world without limitations.

For personalized travel assistance, contact OxiMedical at 1-888-643-4921. Our respiratory specialists are happy to help you plan your trip and ensure you have everything you need for a worry-free experience.

Need help operating your concentrator? We offer phone tech support—call us anytime!

By following this guide, you can confidently travel with your portable oxygen concentrator, knowing that you are well-prepared for a safe and enjoyable trip!

 

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